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Literature summary for 6.3.4.5 extracted from

  • Satoh, M.; Ando, S.; Shinoda, T.; Yamazaki, M.
    Clearance of bacterial lipopolysaccharides and lipid A by the liver and the role of argininosuccinate synthase (2008), Innate Immun., 14, 51-60.
    View publication on PubMed

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
Mus musculus 5829
-

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+
-
Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + L-citrulline + L-aspartate Mus musculus rate-limiting enzyme of the urea cycle AMP + diphosphate + 2-(Nomega-L-arginino)succinate
-
?
additional information Mus musculus ASS binds to and inactivates lipopolysaccharide and lipid A, overview ?
-
?

Organism

Organism UniProt Comment Textmining
Mus musculus
-
male C3H/He, C57BL/6, and BALB/c mice
-

Source Tissue

Source Tissue Comment Organism Textmining
hepatocyte
-
Mus musculus
-
liver
-
Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + L-citrulline + L-aspartate
-
Mus musculus AMP + diphosphate + 2-(Nomega-L-arginino)succinate
-
?
ATP + L-citrulline + L-aspartate rate-limiting enzyme of the urea cycle Mus musculus AMP + diphosphate + 2-(Nomega-L-arginino)succinate
-
?
additional information ASS binds to and inactivates lipopolysaccharide and lipid A, overview Mus musculus ?
-
?

Cofactor

Cofactor Comment Organism Structure
ATP
-
Mus musculus